Like Gaining Perspective for example
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https://forum.weightgaming.com/t/queen-sized-test-verson-1-7-version-9-update3-horny/28709/30
Queen sized - technically, though as far as I remember there isn’t much to do once you are immobile.
and abducted, in which the non-plus version ends at immobility I’m told, and the plus version the immobility ends after a week or so and the aliens give you a genemod to let you continue walking around.
But if you’re asking cause you want the kinda dark depressing stuff then neither of these are that.