I’ve repeatedly come across a bug. If you reach the “trapped in room” milestone while afflicted with food poisoning, stomach distress, or any other illnesses which affect your food intake, those illnesses don’t get cleared out when you hit that milestone. The illnesses also don’t expire after the milestone, no matter how long you continue beyond it. This is in contrast to other injuries/ailments (e.g. fatigue, twisted knee, food coma, etc) which are automatically ended as soon as you hit the “trapped in room” milestone. This happens regardless of whether you’re living with Paul at the time or not.
I’ve also noticed that the text of the “medium ending” still refers to your character as being in their mid-20s, even though the character’s age was increased in a past game update.
A final bug I noticed… if you cheat your way to immobility sometime after day 100, but before you achieve it through normal means, when you go to do a medical study, it gives an absurdly long wait before you’re allowed to undergo the study. I’ve only encountered this once, so I don’t have more info about it.
Edit: one more thing I noticed. It seems the update you posted a couple weeks ago doesn’t show up when you go to “play latest build.” The most recent version of the game available to play is from March of this year.